Section: New Results

Multivariate Analysis for the detection of the effect of a treatment

Participant : Anne Gégout-Petit.

The aim of this work is to give some statistical rules to determine if a patient is meeting a given treatment (a BD here). The criterium commonly used to determine if a patient is meeting a BD treatment is based only on one physiological parameter : if this parameter increases, the patient is meeting. But now, many physiological parameters are measured in routine and it seems that a patient could have a global amelioration of his health state due to the treatment without an increase of the single used parameter.

Using standard multivariate analysis techniques, and classification, we have proposed criteria to discriminate groups of patients different in regard of their response to treatment. This work will be used by physiologists to propose new criteria for the measure of the effect of a BD treatment. It is in collaboration with physiologists from Bordeaux and Nantes universities and is the object of a submitted paper in a international peer-reviewed journal in the domain of pneumology .